Process for the preparation of a carbocyclic nucleoside...

Details Process for the preparation of a carbocyclic nucleoside... Process for the preparation of a carbocyclic nucleoside...

C - Chemistry, Metallurgy

07

H

260/210, 260/229

C07H 19/067 (2006.01) C07D 473/00 (2006.01) C07H 19/16 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2021290

ABSTRACT PROCESS FOR THE PREPARATION OF A CARBOCYCLIC NUCLEOSIDE ANALOGUE A process is described for the preparation of carbocyclic guanosine from aristeromycin in a multi-step procedure, the final step of which is the hydrolysis of a compound of the formula Image (II) wherein R1 represents a C1-6alkyl group or an arylC1-4alkyl group and R2, R3 and R4 each independently represent a hydrogen atom or a hydroxyl protecting group. Carbocyclic guanosine is an intermediate in the synthesis of carbocyclic analogues of nucleosides having use in therapy, particularly as antiviral agents.

Affiliated with

Also associated with

Rating

Process for the preparation of a carbocyclic nucleoside... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of a carbocyclic nucleoside..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of a carbocyclic nucleoside... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2072890