C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
260/212, 530/15.
C08B 37/10 (2006.01) B01J 20/32 (2006.01) C07K 14/81 (2006.01) C08B 37/00 (2006.01) C08B 37/12 (2006.01)
Patent
CA 1334042
A process for the preparation of a material for affinity chromatography is described, in which a sulfated poly- saccharide is bonded to a carrier material which has amino groups. For this purpose, a sulfated polysaccharide is treated with an oxidizing agent which oxidizes glycols to alde- hydes, with cleavage of the carbon chain, and this modi- fied sulfated polysaccharide is allowed to react with a carrier which has amino groups. It is possible using the described affinity material to adsorb proteins which bind to sulfated polysaccharides from solutions of these proteins and, where appropriate, then to desorb them, for example antithrombin III from blood plasma.
509876
Paques Eric-Paul
Stuber Werner
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Csl Behring Gmbh
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