Process for the preparation of a peptide powder form

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 38/26 (2006.01) C07K 14/605 (2006.01)

Patent

CA 2745557

The invention comprises a process for the production of a freely flowable homogenous powder form of a GLP-1 peptide analogue. The process is characterized in that a solution of the peptide analogue in an aqueous organic solvent that is preferably directly obtained from the chromatographic purification process, is subjected to a spray drying process and recovered in the form of a freely flowable homogenous powder.

La présente invention comprend un procédé de production d'une forme pulvérulente homogène fluide d'un analogue de peptide GLP-1. Le procédé est caractérisé en ce qu'une solution de l'analogue peptidique dans un solvant organique aqueux, préférentiellement directement obtenu à partir du procédé de purification chromatographique, est soumise à séchage par atomisation avant d'être récupérée sous la forme d'une poudre homogène fluide.

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