Process for the preparation of a s-2,2-r ,r...

C - Chemistry – Metallurgy – 12 – N

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195/86, 195/1.37

C12N 1/16 (2006.01) C07D 317/20 (2006.01) C12P 17/04 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2020197

ABSTRACT A process for the preparation of S-2,2-R1,R2-1,3-dioxolane- 4-methanol. Process for the preparation of S-2,2-R1,R2-1,3-dioxolane-4- methanol wherein R1 and R2 are each independently H or an alkyl group or wherein R1 and R2 together with the carbon atom to which they are attached form a carbocyclic ring by subjecting a mixture of R- and S-2,2-R1,R2-1,3-dioxolane-4- methanol to the action of a microorganism or substance derived therefrom which is capable of stereoselective consumption of R-2,2-R1,R2-1,3-dioxolane-4-methanol prefer- ably until at least 50 wt% of the R-2,2-R1, R2-1,3-dioxolane- 4-methanol is consumed. Various microorganisms are disclosed as suitable for the purpose.

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