Process for the preparation of a synthetic intermediate for...

Details Process for the preparation of a synthetic intermediate for... Process for the preparation of a synthetic intermediate for...

C - Chemistry, Metallurgy

07

C

C07C 209/74 (2006.01) C07C 209/00 (2006.01) C07C 211/46 (2006.01)

Patent

CA 2503188

Process for the preparation of a compound of general formula (I): in which X represents a halogen atom, by reaction of para-trifluoromethylaniline of formula (II): with a dihalogen x2, the two compounds being introduced simultaneously into a polar aprotic solvent in a dihalogen/compound (II) molar ratio ranging from 1.9 to 2.5 and at a temperature ranging from 100 to 300~ C.

Cette invention a trait à un procédé de préparation d'un composé correspondant à la formule générale (I). Dans cette formule, X représente un atome d'halogène, obtenu par réaction d'une para-trifluorométhylaniline, correspondant à la formule (II), avec un dihalogène x¿2?, les deux composés étant introduits simultanément dans un solvant polaire aprotique dans un dihalogène/composé (II) dont le rapport molaire est compris entre 1,9 et 2,5 et ce, à une température comprise entre 100 et 300C.

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