Process for the preparation of a thiazepine compound

Details Process for the preparation of a thiazepine compound Process for the preparation of a thiazepine compound

C - Chemistry, Metallurgy

07

D

260/238.6

C07D 417/04 (2006.01) C07D 281/16 (2006.01)

Patent

CA 1337345

11-(4-[2-(2-Hydroxyethoxy)ethyl]-piperazinyl)- dibenzo[b,f][1,4]thiazepine and the salts thereof possess antiandropaninergic activity, especially antipyschotic activity, and are prepared by reacting 11-piperazinyldibenzo[b,f][1,4]thiazepine with a compound of the formula:- X-CH2-CH2-O-CH2-CH2OH (wherein X represent an atom or group removable as an anion and, where appropriate further reaction of the product obtained to yield the free base or salt as desired.

559825

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