Process for the preparation of acetamide derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 233/08 (2006.01) C07C 231/00 (2006.01) C07C 319/14 (2006.01) C07C 323/60 (2006.01)

Patent

CA 2378418

PROCESS FOR THE PREPARATION OF ACETAMIDE DERIVATIVES ABSTRACT OF THE DISCLOSURE The invention provides a process for the preparation of diphenylmethylthioacetamide (I) as described in Scheme 4 comprising reacting of the isothiouronium salt or its corresponding base of the formula IV with an acetamide of the formula XCH2CONH2, wherein X represents a halogen, M represents an alkali metal and A represents an anion, in a protic medium at a temperature of less than 100° C. Image

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