Process for the preparation of activated polyethylene glycols

C - Chemistry – Metallurgy – 08 – G

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C08G 65/00 (2006.01) C08G 65/329 (2006.01)

Patent

CA 2457876

The present invention relates to a process for the preparation of activated polyethylene glycols, or PEG(NPC)2s, comprising reacting polyethylene glycol with an activator while in the presence of an aromatic nitrogen containing heterocyclic base. The process is carried out at temperatures ranging from about 20 to about 30 ~C, more preferably at room temperature, and under stoichiometric conditions.

La présente invention porte sur un procédé de préparation de polyéthylèneglycols activés ou PEG(NPC)?2¿, ce procédé consistant à mettre à réagir un polyéthylèneglycol avec un activateur en présence d'une base hétérocyclique aromatique contenant de l'azote. Le procédé est réalisé à des températures comprises entre environ 20 et environ 30 ·C, idéalement à température ambiante, et dans des conditions stoechiométriques.

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