Process for the preparation of adapalene and related compounds

Details Process for the preparation of adapalene and related compounds Process for the preparation of adapalene and related compounds

C - Chemistry, Metallurgy

07

C

C07C 65/26 (2006.01) C07C 43/21 (2006.01) C07C 51/09 (2006.01) C07C 51/347 (2006.01)

Patent

CA 2612497

The invention provides an improved process for the preparation of a benzonaphthalene derivative including, in particular, the manufacture of high purity adapalene. The invention further includes a method for assessing the color of adapalene by means of a quantitative colorimetric measurement of the produced adapalene.

La présente invention concerne un procédé amélioré pour la préparation d'un dérivé benzonaphtalène comprenant, notamment, la fabrication d'adapalène de grande pureté. L'invention concerne également un procédé pour l'évaluation de la couleur d'adapalène au moyen d'une mesure colorimétrique quantitative de l'adapalène produit.

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