Process for the preparation of adenine derivatives made...

Details Process for the preparation of adenine derivatives made... Process for the preparation of adenine derivatives made...

C - Chemistry, Metallurgy

07

H

260/242.3, 260/2

C07H 19/20 (2006.01) C07D 303/48 (2006.01) C07F 9/6561 (2006.01) C07H 19/207 (2006.01)

Patent

CA 1058169

ABSTRACT OF THE DISCLOSURE Adenine of adenine-containing derivatives substituted ? the nitrogen atom, in position 6, of the adenine nucleus with a functional radical having the general formula: Image wherein R is a hydrogen atom or an alkyl radical of 1 to 4 carbon atoms and n is an integer between 1 and 4, are obtained by reacting adenine or a compound containing an adenine nucleus with an epoxy-carboxylic acid or ester of the general formula: Image wherein R and n have the aforesaid meanings, and subjecting the reaction product obtained to a molecular re-arrangement. Adenine- containing compounds are of great importance in biochemistry and the possibility of obtaining functional derivatives thereof widens their field of application.

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