Process for the preparation of .alpha.- aminoalkylphosphonic...

Details Process for the preparation of .alpha.- aminoalkylphosphonic... Process for the preparation of .alpha.- aminoalkylphosphonic...

C - Chemistry, Metallurgy

07

F

260/501

C07F 9/30 (2006.01) C07F 9/38 (2006.01)

Patent

CA 1261347

- 1 - Abstract: .alpha. -Aminoalkylphosphonic and .alpha.-aminoalkylphosphinic acids of the formula I Image (I) uhere n = 1 or 0, R1 = H, CH3 or CH2-C6H5 R2 = H (for n = 1) and also = alkyl or phenyl (for n = O) are prepared by Hofmann degradation from compounds of the formula II (II) Image where n and R1 have the same meaning as in formula I, R3 = alkyl (for n = 1), alkyl or phenyl (for n = 0), and Mp+ = p-valent cation, with subsequent working up in the known manner. Some of the compounds I are biologically active, and some are intermediates for the preparation of biologically active compounds.

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