C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 217/02 (2006.01) C07F 17/02 (2006.01)
Patent
CA 2708889
The present invention relates to a process for the preparation of the compound of formula (7) which process comprises the hydrogenation of the compound of formula (4) using bis[chloro-1,5-cyclooctadiene-iridium], (S)-i-dicyclohexylphosphino-2-[(S)-.alpha.-(dimethy- lamino)-2-(dicyclohexylpho sphino)benzyl] -ferrocene as a catalyst.
La présente invention concerne un procédé pour la préparation d'un composé de formule 7 (7), lequel procédé comprend l'hydrogénation du composé de formule 4 (4) en utilisant du bis[chloro-1,5-cyclooctadiène-iridium], (s)-i-dicyclohexylphosphino-2-[(S)-a-(diméthylamino)-2-(dicyclohexylphosphino)benzyl]-ferrocène comme catalyseur.
Bappert Erhard
de Vries Andreas Hendrikus Maria
Domin Doris
Helms Matthias
Imboden Christoph
Actelion Pharmaceuticals Ltd
Gowling Lafleur Henderson Llp
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