C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/04 (2006.01) C07D 209/42 (2006.01)
Patent
CA 2337382
A process for the preparation of methyl 2-(3-chloropropoxy)-idole-3- carboxylate, which comprises reacting 3-chloro-3-carboxylate indole compound with 3-chloropropanol in the presence of an acid having a pKa of from 0 to 2.
L'invention concerne un procédé de préparation 2-(3-chloropropoxy)-indole-3-carboxylate de méthyle. Ce procédé consiste à faire réagir un composé 3-chloro-3-carboxlyate indole avec du 3-chloropropanol en présence d'un acide présentant un pKa compris entre 0 et 2.
Fedouloff Michael
Strachan John Bryce
Gowling Lafleur Henderson Llp
Smithkline Beecham P.l.c.
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