Process for the preparation of antitumor anthracycline...

Details Process for the preparation of antitumor anthracycline... Process for the preparation of antitumor anthracycline...

C - Chemistry, Metallurgy

07

H

260/208.2

C07H 15/24 (2006.01) C07D 309/30 (2006.01) C07H 13/04 (2006.01) C07H 15/04 (2006.01) C07H 15/252 (2006.01)

Patent

CA 1175420

-64 ABSTRACT OF THF DISCLOSURE A process for the preparation of novel antitumor an- thracycline glycosides by condensing daunomycinone wlth 2,3,4,6- tetradeoxy-4-C-methylene-3-trifluoroacetamido-L-threo-hexopyranosyl chloride; 2,3,4,6-tetradeoxy-4-C-methylene-3-trifluoroacetamido- L-arabino-hexopyranosyl chloride or 2,3,6-trideoxy-4-C-trifluoro- acetamideomethyl-3-trifluoroacetamido-3-0-trifluoroacetyl-L-lyxo- hexopyranosyl chloride.

389151

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