Process for the preparation of aromatic-1,4- oxazepinones...

Details Process for the preparation of aromatic-1,4- oxazepinones... Process for the preparation of aromatic-1,4- oxazepinones...

C - Chemistry, Metallurgy

07

D

260/277, 260/295

C07D 267/12 (2006.01) C07D 213/80 (2006.01) C07D 213/82 (2006.01) C07D 267/14 (2006.01) C07D 498/04 (2006.01)

Patent

CA 1277983

ABSTRACT OF THE DISCLOSURE PROCESS FOR THE PREPARATION OF AROMATIC-1,4-OXZEPINONES AND THIONES A process for the preparation of 1,4-oxazepinones and thiones having the formula: Image wherein A is an optionally substituted aromatic ring selected from benzene, naphthalene, quinoline or pyridine; n is 1 to 3; Z is an amino radical; R is hydrogen, loweralkyl, cycloalkyl or optionally substituted phenylloweralkyl; and R4 and R5 are hydrogen and loweralkyl starting from chloroaromatic carboxylates and alkanolamines is disclosed. New ether and carboxamide intermediate compounds of the process described above having the formulas: Image and Image wherein A, n, Z, R, R4 and R5 have the meanings given above, and X is halogen are also disclosed.

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