Process for the preparation of aromatic amines

Details Process for the preparation of aromatic amines Process for the preparation of aromatic amines

C - Chemistry, Metallurgy

07

C

C07C 209/14 (2006.01) C07B 57/00 (2006.01) C07C 29/143 (2006.01) C07C 209/16 (2006.01) C07C 211/27 (2006.01) C07C 309/66 (2006.01)

Patent

CA 2529152

There is provided a process for the preparation of aromatic amines of Formula (1): where Rx is optionally substituted aryl and Ry is optionally substituted hydrocarbyl, which comprises: (a) reducing a compound of Formula (2): to give a compound of Formula (3): then, (b) reacting a compound of Formula (3) with a leaving group donor, to give a compound of Formula (4); and, (c) reacting a compound of Formula (4) with ammonia to give the compound of Formula (1).

L'invention concerne un procédé de préparation d'amines aromatiques de formule (1), dans laquelle R?x¿ représente aryle éventuellement substitué et R?y¿ représente hydrocarbyle éventuellement substitué. Ledit procédé consiste : (a) à réduire un composé de formule (2) afin d'obtenir un composé de formule (3) puis, (b) à faire réagir un composé de formule (3) avec un donneur de groupe partant afin d'obtenir un composé de formule (4) ; et, (c) à faire réagir un composé de formule (4) avec de l'ammoniac afin d'obtenir le composé de formule (1).

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