Process for the preparation of arylalkylamines and...

Details Process for the preparation of arylalkylamines and... Process for the preparation of arylalkylamines and...

C - Chemistry, Metallurgy

07

C

C07C 213/02 (2006.01) C07C 209/52 (2006.01) C07C 211/27 (2006.01) C07C 215/52 (2006.01) C07C 217/60 (2006.01) C07C 303/22 (2006.01) C07C 309/30 (2006.01) C07C 313/04 (2006.01)

Patent

CA 2057953

ATC-0013 Abstract of the Disclosure Arylalkylamines (as the hydrochloride salt), e.g. tyramine hydrochloride, are prepared by hydrogenating substituted or unsubstituted aryl-.alpha.-oximinoalkyl ketones, e.g. p-hydroxyisonitroacetophenone, in either in an aqueous reaction medium comprising hydrochloric acid, essentially without the presence of a lower alkyl alcohol in said reaction medium, or in an aqueous reaction medium comprising water, hydrochloric acid, and a lower alkyl alcohol, wherein the alcohol comprises less than about 90% by volume of the reaction medium. A substituent on the aryl portion of the aryl-.alpha.-oximinoalkyl ketone must be on a position which activates the aromatic ring.

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