Process for the preparation of arylethylamines and...

Details Process for the preparation of arylethylamines and... Process for the preparation of arylethylamines and...

C - Chemistry, Metallurgy

07

C

C07C 215/52 (2006.01) C07C 209/54 (2006.01) C07C 211/49 (2006.01) C07C 213/02 (2006.01) C07C 217/60 (2006.01) C07C 303/22 (2006.01) C07C 309/46 (2006.01) C07C 313/04 (2006.01)

Patent

CA 2090842

DOCKET NO. N-7338 ABSTRACT OF THE INVENTION This invention provides a process for directly preparing hydrohalide salts of arylethylamines from (.alpha.- chloro-.alpha.-oximino)acetophenones. The process involves hydrogenation in presence of a transition metal catalyst in an organic acid in substantial absence of moisture. The process is illustrated by conversion of 4-hydroxy (.alpha.- chloro-.alpha.-oximino)acetophenone to Tyramine hydrochloride: Image

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