C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/118.5
C07D 499/00 (2006.01)
Patent
CA 1113456
Process for the preparation of azacyclic compounds Abstract of the Disclosure 6-Amino-penam compounds, having an antimicrobial action, of the formula Image (I) in which R1 is an azaoligocycloalkyl radical which is bonded via the ring nitrogen atom and contains at least one endo- bridge atom and a total of 7 to 12 ring atoms and can contain a double bond and/or, if desired, as a further ring hetero-atom, an oxygen atom, or a nitrogen atom which can link the radical X1, where X1 is hydrogen or lower alkyl, and/or, if desired, free, esterified or etherified hydroxyl which is bonded to a ring carbon atom, and in which R2 is free carboxyl or carboxyl esterified by a physiologically detachable group, and salts of such compounds, processes for their preparation, pharmaceutical preparations which contain these compounds, including mixtures of these compounds with other antimicrobial, especially anti- bacterial and/or antiviral, active ingredients and/or additional substances or substance mixtures which alleviate the symptoms in the case of infections, the use of the novel compounds of the formula I and their salts, and of the novel substance mixtures, for combating micro-organisms and the preparation of correspond- ing medicaments by non-chemical means.
303286
Scartazzini Riccardo
Schaffner Karl
Fetherstonhaugh & Co.
Novartis Ag
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