C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 305/14 (2006.01) C07D 405/00 (2006.01) C07D 407/00 (2006.01) C07D 407/12 (2006.01) C07D 409/00 (2006.01) C07D 493/04 (2006.01) C07D 493/08 (2006.01) C07F 7/08 (2006.01)
Patent
CA 2155014
Process for the preparation of a derivative or analog of baccatin III or 10- desacetyl baccatin III having a C2 substituent other than benzoate and/or a C4 substituent other than acetate in which the C2 benzoate substituent and/or the C4 acetate substituent of a derivative of baccatin III or 10-desacetyl baccatin III is/are selectively reduced or hydrolyzed to the corresponding hydroxy group(s) and converted to R31COO- and/or R30COO-, respectively, wherein R30 and R31 are independently H, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, monocyclic aryl or monocyclic heteroaryl.
Holton Robert A.
Kim Seokchan
Suzuki Yukio
Florida State University
Smart & Biggar
LandOfFree
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