Process for the preparation of barium sulfate of increased...

C - Chemistry – Metallurgy – 01 – F

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23/101, 167/35

C01F 11/46 (2006.01) A61K 49/04 (2006.01)

Patent

CA 1224009

ABSTRACT OF THE DISCLOSURE Barium sulfate suitable for the preparation of radiographic contrast agents of increased flowability and density is obtained by a high temperature treatment at 700 to 1,200°C and preferably at 800 to 1,000°C. The barium sulfate so sintered is distinguished by a bulk density of 2.5 to 3 g/ml and its aqueous suspension, containing 200 g of barium sulfate per 100 ml, is distinguished by a viscosity of no more than 1,000 mPas. Radiographic contrast agents containing at least 200 g of sintered barium sulfate per 100 ml are outstandingly suitable for the difficult double contrast visualization of the stomach and gastric mucosa.

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