Process for the preparation of benzothiazepines by...

Details Process for the preparation of benzothiazepines by... Process for the preparation of benzothiazepines by...

C - Chemistry, Metallurgy

07

D

C07D 281/10 (2006.01)

Patent

CA 2068231

A process for the preparation of (2S,3S)-2,3-dihydro-3-hydroxy-2-(4- -methoxyphenyl)-1,5-benzothiazepin-4(5H)-one (compound I) by cycliz- ation of an intermediate of formula (see formula II) wherein R represents a C1-C3 alkyl and the asterisks identify the asymmetric carbon atoms; is described. Compound I is an intermediated useful in the synthesis of Diltiazem.

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