Process for the preparation of bosentan

Details Process for the preparation of bosentan Process for the preparation of bosentan

C - Chemistry, Metallurgy

07

D

C07D 239/52 (2006.01) A61K 31/513 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2752045

The invention concerns a new process for the preparation of bosentan or bosentan monohydrate by reaction of compound of Formula II with ethylene glycol in the presence of potassium bases and the potassium salt of bosentan.

La présente invention concerne un nouveau procédé pour la préparation de bosentan ou de bosentan monohydraté et un nouveau sel de bosentan.

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