Process for the preparation of carbamate and urea derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/388, 260/468

C07D 317/24 (2006.01) C07C 273/18 (2006.01) C07D 235/32 (2006.01) C07D 307/86 (2006.01)

Patent

CA 1068717

ABSTRACT OF THE DISCLOSURE The present invention is based on the surprising recognition that on introducing phosgene into a solution which contains an organic com- pound comprising a secondary amino group and a primary amine, the mixed urea is not formed in the theoretical yield [besides the symmetrical diurea formed in a predominant amount] but particularly when carrying out the reaction under suitable conditions, the mixed ureas are forced by the yield of 80% or above.

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