Process for the preparation of carboxamides of...

Details Process for the preparation of carboxamides of... Process for the preparation of carboxamides of...

C - Chemistry, Metallurgy

07

D

C07D 213/78 (2006.01) C07B 43/06 (2006.01) C07D 213/81 (2006.01) C07D 215/50 (2006.01) C07D 241/24 (2006.01)

Patent

CA 2123731

A process for the preparation of a carboxamide of a nitrogen-containing aromatic heterocyclic compound is described. The novel process is a carbamoylation process wherein the corresponding nitrogen-containing aromatic heterocyclic compound is reacted with formamide in the presence of peroxodisulphuric acid or a peroxodisulphate. The use of a carboxamide of a nitrogen-containing aromatic heterocyclic compound for the preparation of the corresponding carboxylic acid by alkaline hydrolysis is also described.

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