Process for the preparation of cephalosporin derivatives...

Details Process for the preparation of cephalosporin derivatives... Process for the preparation of cephalosporin derivatives...

C - Chemistry, Metallurgy

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C07D 501/34 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/20 (2006.01) C07D 501/36 (2006.01) C07D 501/46 (2006.01) C07D 501/56 (2006.01)

Patent

CA 1281317

ABSTRACT OF THE DISCLOSURE The present invention relates to a process for the preparation of derivatives of the cephalosporin family, of formula: Image (I) in which : X is an oxygen atom or a sulfur atom , n is zero, 1 or 2. . R1, R2 and R3 each designate, independently a hydrogen atom or else R1 and R2 designate a hydrogen atom or a methyl group, and R3 designates a carboxyl or cyclopropyl group, or else . R1 and R2 taken together with the carbon atom to which they are linked form a cyclobutyl or cyclopentyl group and R3 is a carboxyl group. . B is the residue of a primary or secondary amine, said derivatives are useful in therapeutics.

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