Process for the preparation of certain steroids

Details Process for the preparation of certain steroids Process for the preparation of certain steroids

C - Chemistry, Metallurgy

07

J

260/21

C07J 21/00 (2006.01)

Patent

CA 1138432

Abstract Process for the preparation of 17.beta.-hydroxy-3-oxo-17.alpha.-pregn-4-ene- 21-carboxylic acid ?-lactone and 17.beta.-hydroxy-3-oxo-17.alpha.-pregna-4,6-diene- 21-carboxylic acid ?-lactone of the formula: Image (wherein the dotted line between the 6-7 positions indicates the additio- . nal double bond of the latter compound), which are valuable intermediates in the synthesis of spironolactone, using as starting materials androst-5- ene-17-one derivatives and organo-phosphorus compounds.

333718

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