Process for the preparation of chloro-deoxysugars

Details Process for the preparation of chloro-deoxysugars Process for the preparation of chloro-deoxysugars

C - Chemistry, Metallurgy

08

B

260/233.4

C08B 5/02 (2006.01) C07H 5/02 (2006.01)

Patent

CA 1138443

ABSTRACT A process for the preparation of a chlorodeoxy derivative of a reducing aldose having a primary hydroxy group in an exocyclic -CH2OH group, in which the said primary hydroxy group is replaced by a chlorine atom to give a chlorodeoxy reducing sugar with a free anomeric centre, characterised in that the free reducing sugar is reacted with a reagent comprising an N,N-dialkyl (methaniminium) chloride obtained by reacting an N,N-dialkyl formamide with a chlorinating agent.

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