C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/06 (2006.01) A61K 31/506 (2006.01) A61P 37/08 (2006.01)
Patent
CA 2468525
In one embodiment, the present invention discloses a process to directly prepare an unequal ratio of rotamers of an acid salt from a basic compound, by creative choice of a solvent medium. The process is particularly useful in preparing specific rotamers of pharmaceutically useful salts in desired preponderance.
Un mode de réalisation de la présente invention concerne un procédé permettant de préparer directement un rapport inégal de rotamères d'un sel acide à partir d'un composé basique, par choix approprié d'un milieu solvant. Ledit procédé est notamment utile pour préparer des rotamères spécifiques de sels pharmaceutiquement utiles selon une prépondérance souhaitée.
Gala Dinesh
Goodman Andrew J.
Lee Gary
Liao Hongbiao
Schwartz Martin L.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Schering Corporation
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