C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/46 (2006.01) C07C 231/24 (2006.01)
Patent
CA 2223373
The object of the present invention is an industrial process for the purification and removal of residual solvents from iohexol, based on the suspension of crystalline iohexol, eventually containing residual solvents above 100 ppm, in a fluid wherein it has a low solubility, followed by heating, filtration and drying. The process allows the formation of crystalline iohexol with no residual organic residual solvent above 100 ppm and with an increased purity level.
de Carvalho Alexandre Jose Ganchas
Perez Carlos Manuel Alvarez
Villax Guido Du Boulay
Hovione Inter Ltd.
Mccarthy Tetrault Llp
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