Process for the preparation of cyclopropyl carboxylic acid...

C - Chemistry – Metallurgy – 07 – C

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C07C 67/347 (2006.01) C07C 61/04 (2006.01) C07C 69/003 (2006.01) C07C 69/017 (2006.01) C07C 69/743 (2006.01) C07C 69/753 (2006.01) C07C 69/96 (2006.01) C07C 211/40 (2006.01) C07C 233/58 (2006.01) C07C 247/22 (2006.01)

Patent

CA 2408591

The invention relates to a novel process for the preparation of certain cyclopropyl carboxylic acid esters and other cyclopropyl carboxylic acid derivatives; a novel process for the preparation of dimethylsulfoxonium methylide and dimethylsulfonium methylide; to the use of certain cyclopropyl carboxylic acid esters in a process for the preparation of intermediates that can be used in the synthesis of pharmaceutically active entities; and to certain intermediates provided by these processes.

L'invention concerne un nouveau procédé de préparation de certains esters d'acide carboxylique cyclopropyl et d'autres dérivés d'acide carboxylique cyclopropyl. L'invention concerne également un nouveau procédé de préparation de méthylure de diméthylsulfoxonium et de méthylure de diméthylsulfonium, l'utilisation de certains esters d'acide carboxylique cyclopropyl dans un procédé de préparation d'intermédiaires qui peuvent être utilisés dans la synthèse d'éléments pharmaceutiquement actifs, ainsi que certains intermédiaires produits selon ces procédés. The invention relates to a novel process for the preparation of certain cyclopropyl carboxylic acid esters and other cyclopropyl carboxylic acid derivatives; a novel process for the preparation of and; to the use of certain cyclopropyl carboxylic acid esters in a process for the preparation of intermediates that can be used in the synthesis of pharmaceutically active entities; and to certain intermediates provided by these processes.

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