Process for the preparation of (d) 2-(6-methoxy-2-...

Details Process for the preparation of (d) 2-(6-methoxy-2-... Process for the preparation of (d) 2-(6-methoxy-2-...

C - Chemistry, Metallurgy

07

C

260/531.1, 260/6

C07C 59/66 (2006.01) C07C 51/487 (2006.01)

Patent

CA 1207338

ABSTRACT OF THE DISCLOSURE (d)-2-(6-Methoxy-2-naphthyl)propionic acid and pharmaceutically acceptable salts thereof are prepared by resolving mixtures of (d)- and (1)-enantiomers of 2-(6-methoxy-2-naphthyl)propionic precursor acids or salts thereof with N-alkyl- or N-cycloalkyl-D-glucamines or salts thereof to isolate the corresponding (d)-2-(6-methoxy-2-naphthyl)propionic precursor acid which can be readily converted into (d)-2-(6-methoxy-2-naphthyl)propionic acid or a pharmaceutically acceptable salt thereof.

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