Process for the preparation of di-ortho-substituted...

Details Process for the preparation of di-ortho-substituted... Process for the preparation of di-ortho-substituted...

C - Chemistry, Metallurgy

07

C

260/620.5

C07C 37/62 (2006.01) C07C 39/26 (2006.01)

Patent

CA 1276183

ABSTRACT The invention is a process to prepare a 4- (bromo or chloro)methyl-3,5-dihalo-2,6-disubstituted phenol from a 4-methyl-2,6-disubstituted phenol and a brominating or chlorinating agent, in an aprotic organic diluent. The process is highly selective and efficient. For example, high purity 4-bromomethyl-3,5- dibromo-2,6-dimethylphenol can be prepared from 2,4,6- trimethylphenol and bromine, in bromochloromethane at high conversion.

535736

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