Process for the preparation of donepezil and intermediate...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/32 (2006.01)

Patent

CA 2617165

The present invention relates to a new process for the preparation of intermediate compounds useful in the manufacture of donepezil, or a pharmaceutically-acceptable salt thereof, and also relates to processes for preparing donepezil and to the novel intermediates per se. In addition the invention relates to various hydrated forms of donepezil.

La présente invention concerne un nouveau procédé de préparation de composés intermédiaires utilisés dans la fabrication de donepezil, ou un sel pharmaceutiquement acceptable de ceux-ci, et concerne également des procédés de préparation de donepezil et les nouveaux intermédiaires en soi. De plus, l~invention concerne diverses formes d~hydratées de donepezil.

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