Process for the preparation of drug pellets

Details Process for the preparation of drug pellets Process for the preparation of drug pellets

A - Human Necessities

61

K

A61K 9/16 (2006.01) B01J 2/00 (2006.01) B01J 2/10 (2006.01) B01J 2/20 (2006.01) B01J 2/30 (2006.01)

Patent

CA 2146536

The object of the invention is a process for the preparation of drug pellets, which method comprises the stages according to which: a drug containing powder is granulated in a rotor type granulator, by exerting a centrifugal force on the powder in the ro- tor and bringing it, at the periphery of the rotor or adjacent thereto, in contact with a granulating liquid fed separately into the rotor and converted to a mist therein, to which granulating liquid an anti-adhesion agent in an amount of 0.001-5% of the weight of the granulating liquid has been added; the granulate is extruded; and the extrudate obtained is spheronized to pellets which are dried and optionally coated.

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