Process for the preparation of eburnamenine derivatives

Details Process for the preparation of eburnamenine derivatives Process for the preparation of eburnamenine derivatives

C - Chemistry, Metallurgy

07

D

167/231, 260/272

C07D 461/00 (2006.01) A61K 31/435 (2006.01)

Patent

CA 1314286

PROCESS FOR THE PREPARATION OF EBURNAMENINE DERIVATIVES A b s t r a c t The invention relates to the preparation of cis and trans stereoisomers of racemic and optically active eburnamenine derivatives of the general formula (Ia) (Ia) Image or (Ib), Image (Ib) wherein R1 stands for a C1-4 alkyl group; and R stands for hydrogen, a C1-6 alkyl group, a C2-6 alkenyl group, an acyl or substituted acyl group, as well as their acid addition salts, of which the trans compounds are novel.

507055

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