Process for the preparation of enantiomerically enriched...

Details Process for the preparation of enantiomerically enriched... Process for the preparation of enantiomerically enriched...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/44 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2740333

The invention discloses a process for the preparation of compounds having structures typical for proton pump inhibitors in enantiomerically enriched form by using particular metal catalysts in an enantioselective oxidation step. Also disclosed are useful further processes and pure intermediate and subsequently final products.

L'invention porte sur un procédé pour la préparation de composés ayant des structures typiques pour des inhibiteurs de la pompe à protons sous forme enrichie du point de vue des énantiomères à l'aide de catalyseurs métalliques particuliers dans une étape d'oxydation énantiosélective. L'invention porte également sur d'autres procédés utiles et sur un intermédiaire pur et par la suite sur des produits finaux.

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