Process for the preparation of ergoline derivatives

Details Process for the preparation of ergoline derivatives Process for the preparation of ergoline derivatives

C - Chemistry, Metallurgy

07

D

260/206

C07D 457/02 (2006.01) C07D 457/12 (2006.01)

Patent

CA 1205801

TITLE "A process for the preparation of ergoline derivatives" ABSTRACT: R1=H, CH3 R2=H, halogen, CH3, CN, lower alkylthio, phenylthio R7 and R8=H; R3=H, OCH3 R7=H, R3 and R8= bond R7 and R8= bond, R3=H, OCH3 R4=C1-C4 hydrocarbon R5=H, C1-C4 hydrocarbon, Image phenyl A=CHR6, CH2CHR6, CH=CR6 R6=H, lower alkyl n=O, 1,2 X=O,S,NH B=CN, COOalK, CONH2 I Rg=H or B andRg=-?=W W=O,NH and their pharmaceutically acceptable salts are antiprolactinic and antihypertensive agents. Their preparation and pharmaceutical compositions containing them are also described.

452664

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