Process for the preparation of factor x depleted plasma

Details Process for the preparation of factor x depleted plasma Process for the preparation of factor x depleted plasma

C - Chemistry, Metallurgy

12

Q

C12Q 1/56 (2006.01) A61K 35/16 (2006.01) C07K 16/36 (2006.01) C07K 16/40 (2006.01) G01N 33/86 (2006.01) G01N 33/96 (2006.01)

Patent

CA 2143126

A process to prepare factor X deficient plasma is provided. In this process, normal plasma is contacted with an immunoadsor bent having a monoclonal antibody to fac- tor X attached. The factor X binds to the immunoadsorbent and the factor X deficient plasma is collected. The antifactor X antibody immunoadsorbent may be reused. Monoclonal antibodies to factor X are also provided.

Procédé de préparation de plasma appauvri en facteur X. Selon le procédé, on met en contact du plasma normal et un immunoadsorbant auquel est fixé un anticorps monoclonal dirigé contre le facteur X. Le facteur X se lie à l'immunoadsorbant et l'on récupère le plasma appauvri en facteur X. L'immunoadsorbant doté de l'anticorps dirigé contre le facteur X peut être réutilisé. On a également prévu des anticorps monoclonaux dirigés contre le facteur X.

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