Process for the preparation of galanthamine

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 491/06 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2239814

The present invention comprises a process for the preparation of enantiomerically-enriched galanthamine from racemic galanthamine, and a process for increasing the enantiomeric excess of enantiomerically- enriched galanthamine, by direct crystallisation of galanthamine salts.

La présente invention concerne un procédé de préparation de galanthamine enrichie en énantiomères, à partir de galanthamine racémique, ainsi qu'un procédé permettant d'accroître l'excédent énantiomère de galanthamine enrichie en énantiomères par cristallisation directe de sels de galanthamine.

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