Process for the preparation of highly pure crystalline (r,s)...

Details Process for the preparation of highly pure crystalline (r,s)... Process for the preparation of highly pure crystalline (r,s)...

C - Chemistry, Metallurgy

07

D

C07D 501/34 (2006.01) A61K 31/545 (2006.01) A61P 31/04 (2006.01) C07D 501/00 (2006.01)

Patent

CA 2416695

A process for the preparation of highly pure crystalline form of cefuroxime-1- acetoxyethyl ester (cefuroxime axetil) from cefuroxime by reacting an amine salt of cefuroxime with an esterifying reagent.

L'invention concerne un procédé de préparation d'une forme cristalline extrêmement pure de céfuroxime-1-acétoxyéthyl ester (céfuroxime axétil) à partir de céfuroxime en faisant réagir un sel d'amine de céfuroxime avec un réactif d'estérification.

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