Process for the preparation of hpb esters

Details Process for the preparation of hpb esters Process for the preparation of hpb esters

C - Chemistry, Metallurgy

07

C

C07C 67/303 (2006.01) C07C 67/31 (2006.01) C07C 67/317 (2006.01) C07C 69/716 (2006.01) C07C 69/732 (2006.01) C07C 69/738 (2006.01)

Patent

CA 2325737

ghis invention relates to a novel advantageous process for the stereoselective preparation of 2-hydroxy-4-phenylbutyrates (HPB esters) and of their precursors. This is done by starting from readily accessible .alpha.- unsaturated .alpha.-hydroxy-.gamma.-keto esters which can be prepared by Claisen condensation.

L'invention se rapporte à un nouveau procédé avantageux permettant la préparation stéréosélective d'esters d'HPB (2-hydroxy-4-phénylbutyrates) et de leurs précurseurs. Le procédé consiste à démarrer à partir d'esters .alpha.-hydroxy-.gamma.-kéto .alpha.-insaturés que l'on peut préparer par la condensation de Claisen.

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