Process for the preparation of hydrochlorides

Details Process for the preparation of hydrochlorides Process for the preparation of hydrochlorides

C - Chemistry, Metallurgy

07

K

260/100, 260/110

C07K 7/64 (2006.01) C07D 207/22 (2006.01) C07D 211/70 (2006.01) C07D 211/88 (2006.01) C07D 223/26 (2006.01) C07D 489/04 (2006.01) C07D 495/04 (2006.01) C07D 499/00 (2006.01) C07D 501/04 (2006.01) C07H 15/16 (2006.01) C07H 15/20 (2006.01) C07H 15/224 (2006.01) C07H 15/234 (2006.01) C07H 15/238 (2006.01) C07H 15/252 (2006.01) C07H 17/08 (2006.01) C07J 41/00 (2006.01)

Patent

CA 1208626

PROCESS FOR THE PREPARATION OF HYDROCHLIRIDES A b s t r a c t The invention relates to a process for the preparation of hydrochlorides, i.e. of acid addition salts formed with hydrochloric acid, particularly of compounds containing a protonatable nitrogen atom According to the process of the invention a compound useful to form a hydrochloride and being suitably in the form of a derivative containing protonatable nitrogen atom or in the form of a salt is reacted with a sulphonyl compound of the formula Q - SO2 - Cl, wherein Q stands for a hydroxyl, C1-4 alkyl or an aryl group, the latter being optionally substituted by a C1-4 alkyl group, in a solvent, in the presence of an alcohol, whereupon the hydrochloride obtained is recovered in a known manner.

452850

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