Process for the preparation of indole and derivatives thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 209/04 (2006.01)

Patent

CA 1149396

SPECIFICATION Title of the Invention Process for the Preparation of Indole and Derivatives Thereof Abstract of the Disclosure A process for the preparation of indole and derivatives thereof which comprises reacting an aniline with a 1,2-glycol in the vapor phase, the liquid phase or a mixed vapor-liquid phase. Various solid acids, metals and activated carbon can be used as catalysts for this reaction. The present invention makes it possible to prepare indole and derivatives thereof in a single step by using inexpensive compounds as the starting materials.

375857

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