Process for the preparation of intermediate compounds of...

C - Chemistry – Metallurgy – 07 – D

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C07D 221/04 (2006.01)

Patent

CA 2375289

A process for preparing selectively compound (I), (1S, 5S, 6R, 7R)-2-aza-7- chloro-5-methyl-3-oxobicyclo[4.1.0]-heptane, by preparing compound (II) from compound (V) through compound (III) via a series of reactions and crystallizing the obtained compound (II); and the novel intermediate compound represented by the structural formula (III) and hydrate salts thereof.

L'invention concerne un procédé de préparation sélective d'un composé (I), (1S, 5S, 6R, 7R)-2-aza-7-chloro-5-méthyl-3-oxobicyclo[4.1.0]-heptane consistant à obtenir un composé (II) à partir d'un composé (V) à travers un composé (III) via une série de réactions et un procédé de cristallisation du composé obtenu (II). L'invention concerne aussi le nouveau composé intermédiaire représenté par la formule structurelle (III) et ses sels d'hydrate.

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