Process for the preparation of intermediates useful for the...

C - Chemistry – Metallurgy – 12 – P

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C12P 41/00 (2006.01) C07D 281/10 (2006.01) C07D 301/32 (2006.01) C07D 303/48 (2006.01) C07D 407/12 (2006.01) C12P 17/02 (2006.01)

Patent

CA 2042535

A process for the preparation of the compounds of formula (see fig. I) (wherein R has the meanings reported in the specification) by enzymatic transesterification of enantiomeric mixtures is described. These compounds are intermediates useful in the synthesis of Diltiazem.

Méthode pour préparer des composés de formule (voir fig. I) (où R a la signification donnée dans les spécifications), par transestérification enzymatique de mélanges énantiomères. Ces composés sont des intermédiaires utiles pour la synthèse du Diltiazem.

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