Process for the preparation of intermediates useful in the...

Details Process for the preparation of intermediates useful in the... Process for the preparation of intermediates useful in the...

C - Chemistry, Metallurgy

07

D

C07D 311/58 (2006.01) C07C 41/56 (2006.01) C07C 43/303 (2006.01) C07D 311/68 (2006.01) C07D 311/96 (2006.01) C07D 405/02 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 491/052 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2126009

Abstract PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE PREPARATION OF PYRANYL CYANOGUANIDINE DERIVATIVES A process for preparing compound of the formula I Image where a, b, d, R1, R2, R3 and R4 are as defined herein including condensation of a phenol of formula II Image with an acetal of formula III Image in the presence of a catalytic amount of a tertiary amine. The compounds of formula I are intermediates useful in the preparation of pyranyl cyanoguani- dine derivatives which are useful in having potassium channel activating ac- tivity.

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