Process for the preparation of isoxazoloquinoleinone...

C - Chemistry – Metallurgy – 07 – D

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260/273.5

C07D 498/04 (2006.01)

Patent

CA 1225993

PRECIS DE LA DIVULGATION: L'invention concerne la préparation de dérivés de l'isoxazoloquinoléinone de formule générale (I): (I) Image où R est un hydrogène, un fluor, un chlore, un brome, un alkyle linéaire (C1-C5), ramifié (C3-C5), un alkoxy (C1-C5), NO2 ou CF3; et R1 est un phényle éventuellement substitué. L'invention concerne également les dérivés ainsi obtenus. Ces dérivés de formule (I) possèdent de remarquables proprié- tés anxiolytiques et peuvent de ce fait être utilisés comme médicaments.

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