Process for the preparation of levallorphan halomethylates...

C - Chemistry – Metallurgy – 07 – D

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260/237.67

C07D 221/28 (2006.01)

Patent

CA 1220200

ABSTRACT OF THE DISCLOSURE Process for the preparation of levallor- phanhalomethylates by reaction of a methyl halide with levallorphan; products thus obtained having peripheral opiate antagonistic activity and pharmaceutical compos- itions useful to prevent the side effects of opiates, particularly constipation.

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