Process for the preparation of levetiracetam

Details Process for the preparation of levetiracetam Process for the preparation of levetiracetam

C - Chemistry, Metallurgy

07

D

C07D 207/27 (2006.01)

Patent

CA 2657571

The present invention relates to a process for the preparation of levetiracetam and, more particularly, to an improved process for the preparation of levetiracetam characterized by a crystallization-induced dynamic resolution of a diastereoisomeric mixture of an (±)-alpha-ethyl-2-oxo-l -pyrrolidine acetamide derivative.

La présente invention concerne un procédé de préparation de lévétiracétam et, plus particulièrement, un procédé amélioré de préparation de lévétiracétam caractérisé en ce qu'il consiste à réaliser une résolution dynamique induite par cristallisation d'un mélange diastéréoisomérique d'un dérivé de (±)-alpha-éthyl-2-oxo-l-pyrrolidine acétamide.

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